Prof. Dr. Volker Haucke

Volker Haucke

Leibniz Institut für Molekulare Pharmakologie (FMP)
& Freie Universität Berlin
Institut für Pharmazie,
Robert-Rössle-Str. 10
13125 Berlin
Phone: +49 (30) 947 93 100
Fax: +49 (30) 947 93 109
E-mail: haucke@fmp-berlin.de



Position and Status

Professor of Molecular Pharmacology (S-W3), Director of the Leibniz Institut für Molekulare Pharmakologie (FMP)


Scholarships and awards

2020 - Feldberg Prize for Research in Physiology and Pharmacology (announced, prize will be given in 2020)
2017 - Elected Member of The German National Academy of Sciences, Leopoldina
2017 - Avanti Award of the American Society for Biochemistry & Molecular Biology (ASBMB)
2016 - Reinhart-Koselleck-Project of the DFG
2014 - Elected Member of the European Molecular Biology Organization (EMBO)
2003 - Young Investigator Award (YIP), European Molecular Biology Organization (EMBO)
1998 - 1999 - Long-Term Fellowship Award, Human Frontier Science Program
1997 - 1998 - Long-Term Fellowship Award, European Molecular Biology Organization
1995 - Short-Term Fellowship Award, European Molecular Biology Organization
1994 - 1997 - Boehringer Ingelheim Fellow
1993 - 1994 - Dr. Carl-Duisberg-Foundation Scholar
1990 - 1994 - Scholarship Holder of the Studienstiftung des deutschen Volkes



University training and degree

1994 - Diploma in Biochemistry, Freie Universität Berlin
04/1989 - 02/1994 - Study of Biochemistry at Freie Universität Berlin & Univ. of Basel

 

Advanced academic qualifications

2003 - Habilitation (venia legendi) in Biochemistry, Georg-August-Universität Göttingen
1997 - Ph.D. in Biochemistry, Biozentrum, Univ.of Basel (summa cum laude; supervisor: Prof. Dr. G. Schatz)

 

Postgraduate professional career

01/2012 - present - Full Professor of Molecular Pharmacology (S-W3), Freie Universität Berlin & Director of the Leibniz-Institut für Molekulare Pharmakologie; Faculty Member Charité University Medicine Berlin
09/2005 - 12/2011 - Full Professor of Biochemistry (W3), FU Berlin, Institute of Chemistry & Biochemistry, Department of Membrane Biochemistry & Charité Universitätsmedizin Berlin
10/2003 - 08/2005 - Professor of Biochemistry (C3), FU Berlin, Institute of Chemistry & Biochemistry, Department of Membrane Biochemistry
05/2000 - 09/2003 - Head of Independent DFG Junior Research Group, University of Göttingen
04/1997 - 04/2000 - Postdoctoral fellow, Yale University & HHMI (w/ Prof. Pietro De Camilli)

Coordinating functions and editorial work

since 2017 - Scientific Advisory Board, Leibniz Institute on Aging-Fritz Lipmann Institute (FLI)
since 2015 - Scientific Advisory Board of open access platform Matters
since 2012 - Editorial Board Member, EMBO Reports
2007 - 2012 - Editorial Board Member, The Journal of Biological Chemistry
since 2005 - Editorial Board Member, Biology of the Cell
since 2006 - Member, Faculty of 1000, Neuronal Signaling
2008 - 2016 - Member, Study Section, "Biochemistry“ of the German Funding Agency (DFG)
since 2007 - Member & Principal Investigator, NeuroCure Cluster of Excellence
since 2011 - Founding-Chair (now vice-chair) & Member, SFB 958 "Scaffolding of Membranes"
2008 - 2010 - Chair, SFB 449 "Structure and Function of Membrane Integral Receptors"

Most important publications

  1. Wallroth, A., Koch, P.A., Marat, A.L., Krause, E., Haucke, V. (2019) Protein kinase N controls a lysosomal lipid switch to facilitate nutrient signaling via mTORC1. Nature Cell Biol. 21: 1093-1101

  2. Vukoja, A, Rey, U., Petzoldt, A.G., Vollweiter, D., Ott, C., Quentin, C., Puchkov, D., Reynolds, E., Lehmann, M., Hohensee, S., Rosa, S., Lipowsky, R., Sigrist, S.J., Haucke, V. (2018) Presynaptic biogenesis requires axonal transport of lysosome-related vesicles. Neuron 99: 1216-1232.e7

  3. Marat, A.L., Wallroth, A., Lo, W., Müller, R., Norata, G.D., Falsaca, M., Schultz, C., Haucke, V. (2017) mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate. Science, 356: 968-972

  4. Ketel, K., Krauss, M., Nicot, A.S., Puchkov, D., Wieffer, M., Müller, R., Subramanian, D., Schultz, C., Laporte, J., Haucke, V. A phosphoinositide conversion mechanism for exit from endosomes. Nature, 529: 408-412

  5. Kononenko, NL, Puchkov, D, Classen, GA, Walter, A, Pechstein, A, Sawade, L, Kaempf, N, Trimbuch, T, Lorenz, D, Rosenmund, C, Maritzen, M, Haucke, V (2014) Clathrin/ AP-2 mediate synaptic vesicle reformation from endosome-like vacuoles but are not essential for membrane retrieval at central synapses. Neuron 82: 981-988

  6. Daumke, O, Roux, A, Haucke, V (2014) BAR domain scaffolds in dynamin-mediated membrane fission. Cell 156: 882-892

  7. Wilhelm, B.G., Mandad, S., Truckenbrodt, S., Kröhnert, K., Schäfer, C., Rammner, B., Koo, S.J., Claßen, G.A., Krauss, M., Haucke, V., Urlaub, H., Rizzoli, S. O. (2014) Composition of Synaptic Boutons Reveals the Amounts of Vesicle Trafficking Proteins. Science, 344: 1023-1028

  8. Posor, Y, Eichhorn-Grünig, M, Puchkov, D, Schöneberg, J, Ullrich, A, Lampe, A, Müller, R, Zarbakhsh, S, Gulluni, F, Hirsch, E, Krauss, M, Schultz, C, Noe, F, Haucke, V (2013) Spatiotemporal Control of Endocytosis by Phosphatidylinositol 3,4-Bisphosphate. Nature 499: 233-237

  9. von Kleist, L, Stahlschmidt, W, Bulut, H, Gromova, K, Puchkov, D, Robertson, M, MacGregor, KA, Tomilin, N, Pechstein, A, Chau, N, Chircop, M, Sakoff, J, von Kries, J, Saenger, W., Kräusslich, HG, Shupliakov, O, Robinson, PJ, McCluskey, A, Haucke, V (2011) Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition. Cell 146: 471-484

  10. Faelber, K, Posor, Y, Gao, S, Held, M, Roske, Y, Schulze, D, Haucke, V, Noe, F, Daumke, O (2011) Crystal structure of nucleotide-free dynamin. Nature 477: 556-560